Identifying the Causes, Mechanisms and Modern therapies
Introduction
Nasal polyps are non -cancerous and inflammatory appendages inside the nasal cavities and sinuses that can cause problems such as nasal obstruction, decreased smell, and chronic infections.. In recent years, scientific advances in the diagnosis, causes and treatment of this complication have been taken into consideration.. New studies have been more careful about the cellular and molecular mechanisms of nasal polyps and are looking for more effective treatments.. In this article from the site of Dr. Behnam Khorrami (Isfahan nose surgeon _ Jaw surgeon of Isfahan), We will do new research on nasal polyps.
1.. The causes and mechanisms of nasal polyps
The Role of Genetic Factors
Studies have shown that genetic factors in the occurrence Nasal polyps They play an important role. Some genetic mutations associated with chronic inflammation and increased immune cell production such as eosinophils have been observed in patients with nasal polyps. New research using genome sequence has identified specific genes that can contribute to the genetic talent of the disease..
4.3 Chronic inflammation and the role of immune system
Nasal polyps are often associated with chronic inflammation that occur due to over -the -immune activity.. Recent studies have shown that some cytokines and inflammatory factors such as IL-5 and IL-13 have an impact on the development of polyps.. Also, the presence of high IGE and increased immune cells such as eosinophils and yogurts in the nasal mucosa are key factors in the development of this complication..
The effect of environmental factors and allergies
Allergens, air pollution and viral infections can stimulate chronic inflammation in the nose.. Researchers are investigating the effect of air pollution and exposure to chemicals in industrial environments as agents of the disease..
2.. New methods in the diagnosis of nasal polyps
2.3 Using Advanced Imaging Technologies
New advances in medical imaging, including MRI and 3D scans, help physicians examine the exact structure of polyps and evaluate the severity of inflammation.. Also, new studies on the use of optical endoscopy and fluorescence to early diagnosis are underway..
2.3 Biological indicators
New research has focused on identifying bio -blood markers in the blood and nasal fluid to detect nasal polyps. Investigating the level of cytokines, inflammatory proteins, and micro -RNAs can be effective in diagnosing and determining the severity of the disease..
۳. New therapies for nose polyps
2.3 Biological treatments and modern medications
One of the most important advances is the development of biological drugs that purposefully affect inflammatory molecules.. Some new drugs included:
Duplomab (Dupilumab): IL-4 and IL-13 inhibitors, which reduce inflammation and shrink the polyps.
Maplasomab (Mepolizumab) And Benalizomab (Benralizumab): Drugs that act against IL-5 and lower the level of eosinophils.
اومالیزوماب (Omelizbub): A monoclonal antibody operating against IGE and is useful for patients with severe allergies..
2.3 New surgical procedures
Traditional surgery for removing nasal polyps is still a major treatment method, but new techniques such as laser surgery and cold plasma have reduced damage to healthy tissue.. Also, the use of surgical robots and 3D guidance has improved the accuracy of surgical procedures..
The role of nasal microbiomes in the treatment
Recent research has shown that the composition of nasal microbiome (Useful bacteria in the respiratory tract) It can affect inflammation and formation of polyps. Researchers are investigating the use of nasal probiotics to adjust microbial balance and reduce inflammation.
4.. The future of research in the field of nose polyps
Future research will focus on combining various therapies and developing personalized therapies for patients.. Using artificial intelligence and machine learning to predict the likelihood of polyps returning and evaluating patient response to treatments is one of the developing areas. Also, clinical tests on allergy and immunization vaccines may provide new ways to prevent the disease in the future..
Conclusion
New research on nasal polyps has helped to better understand the causes of creating and developing this condition.. Medical advances, including the use of biological drugs, advanced imaging methods, and microbial -based treatments, promise more effective methods for the treatment and prevention of the disease..
Useful links:
Isfahan nose surgeon _ Jaw surgeon of Isfahan
Dr. Behnam Khorrami's page in the clinic 24 | Maxillofacial surgeon in Isfahan clinic 24 | Nose surgeon in Isfahan clinic 24
Dr. Behnam Khorrami, nose surgeon in Isfahan at Dr. Af | Maxillofacial surgeon in Isfahan at Dr. Af | Isfahan nose surgeon at Dr. Af