Therapeutic impacts and strategies

Introduction

Nasal polyps are soft, non -cancerous and inflammatory masses that grow in the internal coating of the nasal ducts or sinuses.. These polyps are usually painless and are caused by chronic inflammation in the upper respiratory system.. Although nasal polyps may exist alone, studies have shown that they are closely associated with some other diseases such as asthma, cystic fibrosis, and allergic rhinitis.. In this article from the site of Dr. Behnam Khorrami (Isfahan nose surgeon _ Jaw surgeon of Isfahan), We deal with nasal polyps with other diseases.

1.. Nasal polyps and its relationship with asthma

۱.۱. Common mechanisms between asthma and nasal polyps

Asthma A chronic inflammatory disease is respiratory tract that causes stenosis of airways and respiratory problems.. Nasal polyps And asthma is both associated with chronic inflammation and increased body immune response. Some of the common mechanisms between these two diseases are:

۲ inflammation: This inflammation, which is caused by increased immune cells such as eosinophils and cytokines such as IL-4, IL-5 and IL-3, is seen in both diseases..

Imbalance in the immune system: In patients with asthma and nasal polyps, abnormal inflammatory responses can lead to inflation of airways and the growth of polyps..

Increased sensitivity to allergens and irritants: People with asthma and nasal polyps are often more susceptible to environmental allergens, leading to exacerbation of symptoms..

۱.۲. The effect of nasal polyps on asthma control

Nasal polyps can disrupt nasal air flow and make breathing difficult.. This may cause patients with asthma to resort to oral breathing, which is itself a cause of asthma attacks.. In addition, nasal polyps may lead to increased inflammation in the lungs and make asthma more difficult to control..

۱.۳. Joint therapeutic Solutions

Using nasal and oral corticosteroids to reduce inflammation

Administration of biological anti -inflammatory drugs such as dupillomab and malasomab to inhibit type 2 inflammation

In severe cases, endoscopic sinus surgery to remove polyps

2.. Cystic fibrosis and its relationship with nose polyps

۲.۱. The role of genetic mutation in the creation of nasal polyps and cystic fibrosis

Cystic fibrosis (Cystic Fibrosis) It is a genetic disease that causes mucosal production and secretion in the lungs and sinuses.. In patients with the disease, the mutation in the CFTR gene causes thick and sticky mucosa to accumulate in air and sinuses.. This situation provides the ground for the growth of nasal polyps.

۲.۲. Complications of nasal polyps in patients with cystic fibrosis

Increase the likelihood of sinus and lung infections

Nasal duct obstruction that leads to a decrease in the quality of life of the patient

Difficulty in breathing that can increase the need for medical interventions such as surgery

۲.۳. Suggested therapies

using Nasal wash With salt serum to reduce mucosal concentration

Inhaled antibiotics to reduce sinus infections

Endoscopic sinus surgery in cases where drug therapies are not effective

۳. Nasal polyps and allergic rhinitis

۳.۱. Clinical similarities between nasal polyps and allergic rhinitis

Allergic rhinitis is a type of chronic nasal inflammation caused by the immune system's excessive reaction to environmental allergens such as flower pollen, dust and animal hair.. Symptoms of the disease include sneezing, nasal cramps, itching and nose secretion. Nasal polyps and allergic rhinitis have the following common characteristics:

Both diseases are caused by over -the -immune system activity.

Chronic inflammation is observed in both.

Patients with allergic rhinitis are more at risk for nasal polyps.

۳.۲. The effect of nasal polyps on the severity of allergic rhinitis

Nasal polyps can exacerbate the symptoms of allergic rhinitis because they block the nasal ducts and make it difficult to exit the secretions.. This increases inflammation and congestion in patients.

۳.۳. Therapeutic solutions

Using antihistamines to reduce allergic reactions

Nasal corticosteroids to reduce inflammation and prevent the growth of polyps

Avoid environmental allergens to reduce nose stimulation

Conclusion

Nasal polyps are closely associated with diseases such as asthma, cystic fibrosis and allergic rhinitis. These communications indicate a common inflammatory path that contributes to the incidence and severity of symptoms.. Management of these diseases requires a multilateral approach including pharmaceutical therapies, environmental factors control, and in severe cases, surgical interventions.

Useful links:

Isfahan nose surgeon _ Jaw surgeon of Isfahan

Dr. Behnam Khorrami's page in the clinic 24 | Maxillofacial surgeon in Isfahan clinic 24 | Nose surgeon in Isfahan clinic 24

Dr. Behnam Khorrami, nose surgeon in Isfahan at Dr. Af | Maxillofacial surgeon in Isfahan at Dr. Af | Isfahan nose surgeon at Dr. Af